Definition Of Gene Ontology
This knowledge is both human readable and machine readable and is a foundation for computational analysis of large scale molecular biology and genetics experiments in biomedical research.
Definition of gene ontology. The evidence codes record the process by which these connections are established and reflect either the experimental analysis of actual instances of gene products or inferential reasoning from such analysis. The gene ontology go provides a framework and set of concepts for describing the functions of gene products from all organisms. Gene ontology annotations report connections between gene products and the biological types that are represented in the go using go evidence codes. A presentation describing the re structuration work of the ontology was given to the apo sys domain experts file 110913 aposys ppm ppt.
The gene ontology go describes our knowledge of the biological domain with respect to three aspects. The experts were asked to have an additional content meeting in the ebi hinxton at some point around october november. Gene ontology overview an ontology is a formal representation of a body of knowledge within a given domain. Maintain and develop its controlled vocabulary of gene and gene product attributes.
More specifically the project aims to. Gene ontology go term enrichment is a technique for interpreting sets of genes making use of the gene ontology system of classification in which genes are assigned to a set of predefined bins depending on their functional characteristics. 1 maintain and develop its controlled vocabulary of gene and gene product attributes. 2 annotate genes and gene products and assimilate and disseminate annotation data.
The gene ontology or go is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. And 3 provide tools for easy access to all aspects of the data provided by the project and to enable functional interpretation of experimental data us. The gene ontology is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. But the idea was finally dismissed due to incompatibility of agendas.
It is specifically designed for supporting the computational representation of biological systems. Ontologies usually consist of a set of classes or terms or concepts with relations that operate between them. As go is routinely updated it serves as the gold standard and main knowledge source in functional genomics.